To work hard or make a great effort.

To suffer from physical or emotional distress, often used in a medical context.

शारीरिक या भावनात्मक चिंता से ग्रस्त होना

English Usage: He labored under the pressure of his responsibilities.

Hindi Usage: वह अपनी जिम्मेदारियों के दबाव से ग्रस्त था।