In a manner that cannot be recovered or regained.

In a way that causes permanent damage or injury.

स्थायी क्षति या चोट के रूप में.

English Usage: The ecosystem was irrecoverably harmed by pollution.

Hindi Usage: प्रदूषण के कारण पारिस्थितिकी तंत्र को स्थायी क्षति पहुँची.