To make an estimate or conjecture
अटकल लगाना
English Usage: I just can't guess the answer to this question.
Hindi Usage: मैं इस सवाल का जवाब अटकल से नहीं लगा सकता।
An estimation or supposition made without complete information
अनुमान
English Usage: My guess is that it will rain tomorrow.
Hindi Usage: मेरा अनुमान है कि कल बारिश होगी।