To infect or spoil gradually.

To have a debilitating effect, often related to feelings or morals.

ऐसे प्रभाव रखना जो सेहत या नैतिकता को कमजोर करे।

English Usage: His guilt cankered his conscience, making it hard for him to sleep.

Hindi Usage: उसकी गलती ने उसकी आत्मा को कमजोर कर दिया, जिससे उसे सोना मुश्किल हो गया।